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Prevalence of cytomegalovirus antibody in Thai-northeastern blood donors.

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Department of Clinical Immunology, Faculty of Associated Medical Sciences, Khon Kaen University, Thailand.


The prevalence of cytomegalovirus antibody was studied in sera of 359 Northeastern blood donors with an age range of 17-59 years by ELISA for anti-CMV total antibody (anti-CMV). Anti-CMV was detected in 93.31% (335/359) of blood donors. The prevalence in males was 91.53% (227 in 248) while female donors showed 97.30% (108 in 111) positive for anti-CMV. The results demonstrated no statistical difference between sex and age. One-hundred and eighty serum samples with positive anti-CMV were reexamined for anti-CMV IgM antibody. Only one sample was found to be positive. This study suggested that CMV seronegative blood supply was very limited. Therefore leukocyte-depleted blood should be the method of choice for prevention of post-transfusion CMV infections in high risk recipients.

[Indexed for MEDLINE]

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