Format

Send to

Choose Destination
Mol Cell Probes. 1994 Oct;8(5):357-64.

Evaluation of nested polymerase chain methods for the detection of human coronaviruses 229E and OC43.

Author information

1
Department of Child Health, University of Leicester, UK.

Abstract

Currently, the diagnosis of human respiratory coronavirus infection is either slow or insensitive. This paper describes nested polymerase chain reaction assays for the detection of human coronaviruses OC43 and 229E. The specificity and sensitivity of the assays have been determined and they have been applied to the detection of the viruses in nasal aspirates. These assays are more rapid and sensitive than cell culture and may replace the latter as the diagnostic method of choice.

PMID:
7877631
DOI:
10.1006/mcpr.1994.1052
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center