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Clin Lab Med. 1994 Dec;14(4):781-94.

Laboratory diagnosis of von Willebrand's disease.

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Hematology Service, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland.


The diagnosis of von Willebrand's disease is becoming complex as more is understood about the disease. Clinical information and laboratory data are necessary for the diagnosis because of the overlap of normal and abnormal laboratory values. A complete evaluation including von Willebrand factor multimers, ristocetin-induced platelet aggregation, factor VIII activity level, and a template bleeding time is necessary to correctly classify the patient so that optimal treatment may be given.

[Indexed for MEDLINE]

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