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Trends Genet. 1994 Dec;10(12):436-40.

GAPs for rho-related GTPases.

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1
MRC Laboratory for Molecular Cell Biology, University College London, UK.

Abstract

Ras-related GTP-binding proteins (GTPases) of the rho subfamily play important roles in regulating the organization of the actin cytoskeleton. A large number of multifunctional proteins that can stimulate their intrinsic GTPase activity have been identified. Here, we discuss the nature of such GTPase-activating proteins (GAPs) and their potential importance for cell signalling.

PMID:
7871593
[Indexed for MEDLINE]
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