Format

Send to

Choose Destination
Vet Res Commun. 1994;18(5):367-72.

Caffeine clearance in the horse.

Author information

1
Department of Large Animal Surgery and Medicine, College of Veterinary Medicine, Auburn University, AL 36849-5522.

Abstract

The pharmacokinetic properties of intravenously administered caffeine were studied in 10 horses using a commercially available automated enzyme immunoassay. The harmonic mean for the distribution half-life was 5.2 min (range 1.4-18.7). The harmonic mean for the elimination half-life was 10.18 h (range 6.82-20.92). The harmonic mean of the volume of distribution was 0.32 L/kg (range 0.22-0.53). There was no correlation between the dose of caffeine/kg body weight and the elimination half-life (Spearman's coefficient of rank correlation = 0.19).

PMID:
7863608
DOI:
10.1007/bf01839287
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center