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Bioorg Med Chem. 1994 Jul;2(7):573-88.

Carba analogues of triglycerides--isosteric mimics for natural lipids. Novel substrates for the determination of regio- and enantioselectivities displayed by lipases.

Author information

1
Bergische Universit├Ąt-GH-Wuppertal, Germany.

Abstract

The novel carba analogues 1a,b and 2 were synthesized and demonstrated to be isosteric identical mimics for natural triglycerides. They can be used for the system independent determination of regio- and enantioselectivities displayed by lipases. They are, moreover, attractive starting materials for novel carba analogues of phospholipids, PAF analogues and PAF antagonists.

PMID:
7858962
DOI:
10.1016/0968-0896(94)85004-6
[Indexed for MEDLINE]

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