The annual report of the Extracorporeal Life Support Organization is presented for 1994. The aggregate experience of neonatal, pediatric pulmonary, and neonatal/pediatric cardiac patients treated with extracorporeal membrane oxygenation is presented for data collected to April 1994. In addition, the Registry now includes a large number of adult extracorporeal membrane oxygenation cases. Rates of survival for each patient group remained unchanged from previous years with 81% neonatal, 50% pediatric, and 44% cardiac survival. Complete data are available through 1992, with increasing case numbers each year as a basis for this growing registry.