[The intrathecal synthesis of G-class immunoglobulins in neurological cancer patients]

Zh Nevrol Psikhiatr Im S S Korsakova. 1994;94(4):42-3.
[Article in Russian]

Abstract

The authors show that brain tumors onset and relevant recurrences are closely related to enhanced synthesis of IgG in the liquor and of circulating immune complexes as well as to blocking factors registered in the liquor. The above facts illustrate autoimmune reactions involved in pathogenesis and recurrent growth of brain tumors. Surgical removal of the latter inhibits the intensity of IgG intrathecal synthesis.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Antigen-Antibody Complex / cerebrospinal fluid
  • Autoimmunity
  • Brain Neoplasms / cerebrospinal fluid
  • Brain Neoplasms / immunology*
  • Cell Migration Inhibition
  • Humans
  • Immunoglobulin G / biosynthesis*
  • Immunoglobulin G / cerebrospinal fluid
  • Neoplasm Recurrence, Local / cerebrospinal fluid
  • Neoplasm Recurrence, Local / immunology
  • Osteochondritis / cerebrospinal fluid
  • Osteochondritis / immunology

Substances

  • Antigen-Antibody Complex
  • Immunoglobulin G