Format

Send to

Choose Destination
Trends Microbiol. 1994 Oct;2(10):361-6.

Origin and molecular epidemiology of penicillin-binding-protein-mediated resistance to beta-lactam antibiotics.

Author information

1
Microbial Genetics Group, School of Biological Sciences, University of Sussex, Brighton, UK.

Abstract

Resistance to beta-lactam antibiotics in some naturally transformable bacterial pathogens has arisen by interspecies recombinational events that have generated hybrid penicillin-binding proteins with reduced affinity for the antibiotics. This type of resistance is of particular concern in pneumococci, in which it is increasing worldwide.

PMID:
7850202
DOI:
10.1016/0966-842x(94)90612-2
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center