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Neuroradiology. 1994 Oct;36(7):537-46.

Experimental saccular aneurysms. I. Review of surgically-constructed models and their laboratory applications.

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Endovascular Therapy Service, University of California, Los Angeles Medical Center.

Erratum in

  • Neuroradiology 1995 Feb;37(2):176.


Experimental models of intracranial saccular aneurysms are a useful contribution to our basic understanding of these lesions. Currently, the commonest in use are those constructed surgically in laboratory animals. We review the numerous surgical techniques available since the 1950s, and the research applications and uses of experimental aneurysms. Further development and use of such models is greatly encouraged in future pathophysiological, hemodynamic, and therapeutic investigations of intracranial saccular aneurysms.

[Indexed for MEDLINE]

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