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Br J Cancer. 1995 Feb;71(2):354-6.

Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer.

Author information

1
Department of Gynecology and Obstetrics, Catholic University, Rome, Italy.

Abstract

High levels of IL-6 were found in 50% of 114 patients with primary ovarian cancer. IL-6 sensitivity was lower than that of CA 125, and the combination of both assays did not increase the sensitivity of CA 125 alone. However, elevated IL-6 serum levels were correlated with a poor prognosis since patients with low IL-6 levels had a better survival than patients with high IL-6 levels (P = 0.0009). Multivariate analysis revealed that IL-6 positivity has an independent value.

PMID:
7841052
PMCID:
PMC2033591
DOI:
10.1038/bjc.1995.71
[Indexed for MEDLINE]
Free PMC Article

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