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Surg Neurol. 1994 Dec;42(6):469-70.

Urokinase thrombolytic therapy of pulmonary embolism in neurosurgically treated patients.

Author information

1
Department of Neurosurgery, Galliera Hospital, Genoa, Italy.

Abstract

Pulmonary embolism (PE) is a severe complication in neurosurgery. The best treatment of PE is thrombolytic therapy, but the presence of either intracranial neoplasm or recent neurosurgical procedures is considered a major contraindication to this therapy. We have used urokinase thrombolytic therapy in nine of our patients with severe PE that occurred from 7 to 34 days after a neurosurgical operation. All patients survived. No intracranial hemorrhage occurred. We also advocate thrombolytic therapy for severe PE in patients who were recently operated on by neurosurgical procedure.

PMID:
7825099
DOI:
10.1016/0090-3019(94)90074-4
[Indexed for MEDLINE]

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