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Rheumatol Int. 1994;14(2):77-81.

Anti-inflammatory effects of recombinant human manganese superoxide dismutase on adjuvant arthritis in rats.

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1
Department of Clinical Immunology, Kyushu University, Beppu, Japan.

Abstract

The anti-inflammatory effects of recombinant human manganese superoxide dismutase on adjuvant arthritis was investigated. Local application of this manganese superoxide dismutase given every 2 days not only significantly reduced foot swelling but also retarded radiological bone destruction in adjuvant arthritis. Copper zinc superoxide dismutase had little effect on foot swelling.

PMID:
7824839
[Indexed for MEDLINE]

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