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J Antimicrob Chemother. 1994 Aug;34(2):261-5.

In-vitro activity of new sulphanilil fluoroquinolones against Staphylococcus aureus.

Author information

1
Departamento de Farmacia, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Argentina.

Abstract

Two new quinolones, NSFQ-104 and NSFQ-105, derivatives of ciprofloxacin and norfloxacin with a 4-(4-aminophenylsulphonyl)-1-piperazinyl at position 7 showed better in-vitro activity against strains of methicillin-susceptible and methicillin-resistant Staphylococcus aureus than ciprofloxacin or norfloxacin. Their in-vitro activity was enhanced at pH 5.5.

PMID:
7814287
DOI:
10.1093/jac/34.2.261
[Indexed for MEDLINE]

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