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Brain Res. 1995 Mar 27;675(1-2):329-32.

Herpes simplex virus induces Fos expression in rat brainstem neurons.

Author information

1
Department of Medicine, Flinders University, Bedford Park, Australia.

Abstract

After the injection of Herpes Simplex Virus type 1 into the rat cervical vagus nerve, transneuronally labelled virus-containing neurons and glial cells were present in the medulla oblongata. Fos-containing nuclei were present in the same regions of the brain. A double-labelling procedure revealed that most of the virus-positive neurons also contained Fos-positive nuclei. Appearance of HSV1 antigen within the CNS is associated with Fos expression in neurons and glial cells.

PMID:
7796147
DOI:
10.1016/0006-8993(95)00016-j
[Indexed for MEDLINE]

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