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Life Sci. 1995;56(23-24):2097-102.

An efficient new cannabinoid antiemetic in pediatric oncology.

Author information

1
Department of Pediatrics, Shaare Zedek Hospital, Jerusalem, Israel.

Abstract

Delta-8-tetrahydrocannabinol (delta-8-THC), a cannabinoid with lower psychotropic potency than the main Cannabis constituent, delta-9-tetrahydrocannabinol (delta-9-THC), was administered (18 mg/m2 in edible oil, p.o.) to eight children, aged 3-13 years with various hematologic cancers, treated with different antineoplastic drugs for up to 8 months. The total number of treatments with delta-8-THC so far is 480. The THC treatment started two hours before each antineoplastic treatment and was continued every 6 hrs for 24 hours. Vomiting was completely prevented. The side effects observed were negligible.

PMID:
7776837
DOI:
10.1016/0024-3205(95)00194-b
[Indexed for MEDLINE]

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