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Trends Microbiol. 1995 Mar;3(3):98-104.

The fungal cell wall as a drug target.

Author information

1
Dept of Oncology, Roche Research Center, Nutley, NJ 07110, USA.

Abstract

Fungal infections are increasingly common and, in certain vulnerable patients, can be serious and even life threatening. The fungal cell wall, a structure with no mammalian counterpart, presents an attractive therapeutic target. Inhibitors of the synthesis of one cell-wall component, beta-(1,3)-glucan, are currently under development as antifungal and antipneumocystis agents.

PMID:
7773595
DOI:
10.1016/s0966-842x(00)88890-3
[Indexed for MEDLINE]

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