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Biochim Biophys Acta. 1995 May 17;1262(1):91-4.

Molecular cloning, sequencing and expression of a cDNA encoding a human liver NAD-dependent alpha-glycerol-3-phosphate dehydrogenase.

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1
Department of Physiopathology and Human Molecular Genetics, Centro de Investigaciones Biológicas, CSIC, Madrid, Spain.

Abstract

This work reports the primary nucleotide structure and in vitro translation of a cDNA, expressed by a gene mapping on chromosome 12, that encodes a human hepatic alpha-glycerol-3-phosphate dehydrogenase (L-glycerol-3-phosphate:NAD oxidoreductase, E.C. 1.1.1.8). The 1413 bp cDNA comprises an ORF of 1050 bp that encodes a 349 amino acid protein of 37.5 kDa. Northern blot analysis of poly(A)+ mRNA from human liver showed three transcripts, while from human placenta only two transcripts were detected.

PMID:
7772607
DOI:
10.1016/0167-4781(95)00069-s
[Indexed for MEDLINE]

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