Format

Send to

Choose Destination
Curr Opin Immunol. 1995 Feb;7(1):77-84.

Molecular chaperones in antigen presentation.

Author information

1
Department of Biochemistry, University of Toronto, Ontario, Canada.

Abstract

As is the case with most proteins of the secretory pathway, the biogenesis of MHC class I and class II molecules occurs in association with molecular chaperones. Considerable progress has been made in identifying the chaperones involved and recent studies on two of these, calnexin and invariant chain, have shown that they influence multiple processes including protein stability, folding, assembly and intercellular retention.

PMID:
7772285
DOI:
10.1016/0952-7915(95)80032-8
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center