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Yeast. 1994 Sep;10(9):1195-202.

Molecular characterization of a gene that confers 2-deoxyglucose resistance in yeast.

Author information

1
Instituto de Agroquímica y Tecnología de los Alimentos (CSIC), Valencia, Spain.

Abstract

We have isolated a gene whose expression enables yeast cells to overcome the inhibition of growth produced by the presence of 2-deoxyglucose. The gene contains an open reading frame of 738 bp that may code for a protein of 27,100 Da. Cells carrying this gene contain high levels of a specific 2-deoxyglucose-6-phosphate phosphatase. The expression of this phosphatase is increased by the presence of 2-deoxyglucose and is constant along the growth curve.

PMID:
7754708
DOI:
10.1002/yea.320100907
[Indexed for MEDLINE]
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