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Am J Med Genet. 1995 Mar 13;56(1):112-5.

Tumors in Rubinstein-Taybi syndrome.

Author information

1
Clinical Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20892-7360, USA.

Abstract

The 14 tumors reported in Rubinstein-Taybi syndrome since 1989, when added to the 22 previously reported, are beginning to show a pattern of neural and developmental tumors, especially of the head, which is malformed in the syndrome. Among the neoplasms were 12 of the nervous system: 2 each of oligodendroglioma, medulloblastoma, neuroblastoma, and benign meningioma, a pheochromocytoma, and 3 other benign tumors; 2 of nasopharyngeal rhabdomyosarcoma; and 1 each of leiomyosarcoma, seminoma, and embryonal carcinoma. Among the other benign tumors were an odontoma, a choristoma, a dermoid cyst, and 2 pilomatrixomas.

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PMID:
7747773
DOI:
10.1002/ajmg.1320560125
[Indexed for MEDLINE]

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