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Structure. 1995 Feb 15;3(2):131-4.

Recombining the structures of HIV integrase, RuvC and RNase H.

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1
Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University, New Haven, CT 06520, USA.

Abstract

The recently reported crystal structures of two recombination enzymes, the catalytic domain of HIV integrase and Escherichia coli RuvC, an endonuclease, are surprisingly similar to that of ribonuclease H suggesting the possibility that they have a common enzymatic mechanism.

PMID:
7735828
[Indexed for MEDLINE]
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