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Genomics. 1994 Nov 15;24(2):366-9.

Characterization and mapping of the Rapsn gene encoding the 43-kDa acetylcholine receptor-associated protein.

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1
Department of Molecular Biology and Pharmacology, Washington University Medical School, St. Louis, Missouri 63110.

Abstract

We have cloned and characterized mouse genomic DNA containing the gene for the 43-kDa acetylcholine receptor-associated protein. The gene extends over 12 kb and consists of 8 exons. RNase protection and sequence analysis have been used to define the intron/exon boundaries including 174 and 214 bp of 5' and 3' untranslated sequence in exons 1 and 8, respectively. Interestingly, the exon/intron organization is consistent with structural domains predicted from amino acid sequence conservation among 3 species of 43K. Finally, the 43K locus, designated Rapsn, has been mapped to the central region of mouse chromosome 2.

PMID:
7698761
DOI:
10.1006/geno.1994.1629
[Indexed for MEDLINE]
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