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FEBS Lett. 1993 Aug 23;329(1-2):134-8.

Primary structure and functional expression of a cyclic nucleotide-gated channel from rabbit aorta.

Author information

1
Institut für Pharmakologie und Toxikologie, Technischen Universität München, Germany.

Abstract

Sequences specific for cyclic nucleotide-gated channels (CNG channels) have been amplified by PCR from cDNA of heart, aorta, sino-atrial node, cerebellum, C-cells and kidney. The complete amino acid sequence of a CNG channel from rabbit aorta has been deduced by cloning and sequence analysis of the cDNA. Synthetic RNA derived from this cDNA induces the formation of a functional CNG channel in Xenopus oocytes.

PMID:
7689061
DOI:
10.1016/0014-5793(93)80209-d
[Indexed for MEDLINE]
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