Control of basophil degranulation

Int J Biomed Comput. 1993 Mar;32(2):151-9. doi: 10.1016/0020-7101(93)90053-9.

Abstract

We first present a linear compartmental model describing human basophiol degranulation by means of an antigen concentration. Then we study an optimal control problem associated to this linear compartmental model in presence of high dilutions. For solving this control problem we used the LAPLACE transform.

MeSH terms

  • Antigens / immunology
  • Basophils / metabolism
  • Basophils / physiology*
  • Calcium / metabolism
  • Cell Degranulation / physiology*
  • Cell Membrane / metabolism
  • Cytoplasmic Granules / physiology
  • Histamine Release / physiology
  • Humans
  • Mathematics
  • Models, Biological*

Substances

  • Antigens
  • Calcium