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Tierarztl Prax. 1995 Jun;23(3):236-40.

[C-reactive protein (CRP)--an acute-phase protein with importance in laboratory medicine in veterinary medicine].

[Article in German]

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Institut für Bakteriologie und Mykologie der Veterinärmedizinischen Fakultät der Universität Leipzig.


CRP is an acute phase protein (APP) formed by hepatic cells in acute phase reaction (APR). APR is initiated by a broad spectrum of cytokines of activated macrophages of blood and tissues. During the APR, plasma concentrations of APP are changed. Cytokines regulate APPs. CRP is a phylogenetically very old molecule. The degree of homology of amino acids in CRP is very high in a lot of species. CRP binding specificities depend on Ca++. The diagnostic importance of CRP in veterinary medicine is discussed.

[Indexed for MEDLINE]

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