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J Rheumatol. 1995 Jun;22(6):1166-70.

Breast feeding and the development of juvenile rheumatoid arthritis.

Author information

1
Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.

Abstract

OBJECTIVE:

To determine if children with juvenile rheumatoid arthritis (JRA) are less likely to have been breast fed than controls.

METHODS:

Case-control study of data obtained from a survey of mothers 54 children with JRA and 79 playmates regarding breast feeding. Duration of breast feeding was tabulated and odds ratios (OR) with 95% confidence intervals (CI) were determined.

RESULTS:

OR for breast feeding in children with JRA was 0.40 (0.20-0.81, 95% CI) compared to playmates. For pauciarticular JRA (N = 28) OR was 0.31 (0.10-0.93); in polyarticular JRA (N = 24) OR was 0.60 (0.21-1.70). Lower OR for increased durations of breast feeding were noted in children with JRA.

CONCLUSION:

Children who have had JRA, especially pauciarticular JRA, are less likely to have been breast fed than controls, suggesting that breast feeding may have a protective effect on the development of JRA.

PMID:
7674248
[Indexed for MEDLINE]

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