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Hum Mol Genet. 1995 Jun;4(6):1073-6.

Linkage of a gene for dominant non-syndromic deafness to chromosome 19.

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Department of Otolaryngology, University of Iowa, Iowa City 52242, USA.


Inherited hearing impairment can occur either in the presence of other clinical features (syndromic hearing loss, SHL) or in isolation (non-syndromic hearing loss, NSHL). The latter is more common and is highly heterogeneous. To date, six NSHL loci have been mapped. We report the identification of a seventh locus (DFNA4) on chromosome 19q13 and suggest DM kinase as a possible candidate gene.

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