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FEMS Microbiol Rev. 1995 Jul;16(4):323-47.

Polysaccharide lyases.

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1
Institute of Cell and Molecular Biology, Edinburgh University, UK.

Abstract

Polysaccharide lyases are the products of various microorganisms, bacteriophage and some eukaryotes. All such enzymes cleave a hexose-1,4-alpha- or beta-uronic acid sequence by beta-elimination. They are in some examples, the only known type of enzymes degrading their polyanionic substrates. Although only a small number of these enzymes have been exhaustively studied, the pectin lyases of bacterial origin have proved to be of interesting crystal structure containing a parallel beta-helix domain. Alginate and heparin lyases may yield products with biotechnological potential.

PMID:
7654407
[Indexed for MEDLINE]
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