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Am J Psychiatry. 1995 Sep;152(9):1368-71.

Sertraline for social phobia: a double-blind, placebo-controlled crossover study.

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1
Foundation for Health, Research and Education, Madison, WI 53717, USA.

Abstract

OBJECTIVE:

The authors examined the efficacy of sertraline in the treatment of social phobia.

METHOD:

In a double-blind crossover study, 12 outpatients were randomly assigned to 10 weeks of sertraline (50-200 mg/day, flexible dosing) and 10 weeks of placebo.

RESULTS:

A statistically significant improvement in scores on the Liebowitz Social Anxiety Scale was found with sertraline but not with placebo. There was no significant difference between scores obtained with computer- and clinician-administered versions of the Liebowitz Social Anxiety Scale, and the majority of patients preferred to be interviewed by the computer.

CONCLUSIONS:

Sertraline seems a safe and effective treatment for social phobia, and computer administration may be a preferable mode of assessment with socially phobic patients.

PMID:
7653696
DOI:
10.1176/ajp.152.9.1368
[Indexed for MEDLINE]
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