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Hypertension. 1995 Sep;26(3):503-8.

Noninvasive pulse wave analysis for the early detection of vascular disease.

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Cardiovascular Division, University of Minnesota Medical School, Minneapolis 55455, USA.


A noninvasive technique has been developed and validated for calculating capacitive and oscillatory systemic arterial compliance with the use of pulse wave analysis and a modified Windkessel model. Application of the technique to subjects with hypertension, postmenopausal women with symptomatic coronary artery disease, and appropriate control subjects has confirmed a reduction of oscillatory compliance in the disease states and an increase in capacitive and oscillatory compliances in response to vasodilator drugs. This method should be useful in screening subjects for early evidence of vascular disease and in monitoring the response to therapy.

[Indexed for MEDLINE]

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