Format

Send to

Choose Destination
See comment in PubMed Commons below
Funct Neurol. 1995 Jan-Feb;10(1):37-44.

The D2 dopamine receptor gene as a predictor of compulsive disease: Bayes' theorem.

Author information

1
Department of Pharmacology, University of Texas Health Science Center, San Antonio 78284, USA.

Abstract

The dopaminergic system, and in particular the dopamine D2 receptor, has been profoundly implicated in reward mechanisms in the meso-limbic circuitry of the brain. Dysfunction of the D2 dopamine receptors leads to aberrant substance (alcohol, drug, tobacco and food) seeking behavior. Decades of research indicate that genetics play an important role in vulnerability to severe substance seeking behavior. We propose that variants of the D2 dopamine receptor gene are important common genetic determinants in predicting compulsive disease.

PMID:
7649500
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center