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Curr Opin Struct Biol. 1995 Apr;5(2):157-64.

Virus structures and conformational rearrangements.

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Howard Hughes Medical Institute, Harvard University, Cambridge, USA.


Structural virology is a burgeoning subspecialty. Our understanding of the molecular organization of viruses has begun to contribute directly to the analysis of viral attachment and entry, assembly, antigenicity, and even viral pathogenesis, but there are still more puzzles than answers. Recent crystallographic results have helped us to understand the structural changes in viruses that affect their assembly and infectivity.

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