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Semin Cancer Biol. 1995 Apr;6(2):63-72.

Cyclins, CDKs and cancer.

Author information

1
Wellcome/CRC Institute, Cambridge, UK.

Abstract

The connections between cancer and the basic machinery of the cell cycle have taken a surprisingly long time to become apparent. However, the past 2 years has seen a dramatic increase in the number of cell cycles regulators that have been implicated as either protooncogenes or as tumour suppressor genes. In this review I will attempt to show how perturbations in the known cell cycle regulators may play a part in the process of oncogenesis.

PMID:
7647308
DOI:
10.1006/scbi.1995.0009
[Indexed for MEDLINE]

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