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Hosp Pract (1995). 1995 Aug 15;30(8):57-8, 60-2, 64-5.

Ternary complex therapy for autoimmune disease.

Author information

1
Division of Immunology and Rheumatology, Stanford University Medical School, USA.

Abstract

Induction of an immune response is remarkably simple, involving the interaction of three components: processed antigen, an MHC class II molecule, and a CD4 T-cell receptor. Each part of this ternary complex represents a novel target for interventions that may block subsequent effector phenomena of autoimmune disease. Such specific treatments will be less toxic than those currently available.

PMID:
7635912
[Indexed for MEDLINE]

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