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Nature. 1979 Mar 1;278(5699):30-4.

A novel bacteriophage defence mechanism: the anti-restriction protein.

Abstract

Bacteriophage T3 and T7 protect their DNA from restriction by producing, as the earliest detectable phage functions, anti-restriction proteins. Although the two phage proteins differ in their chromatographic and antigenic properties, they act by the same mechanism: the anti-restriction proteins inhibit E. coli K12 restriction endonuclease by direct interaction.

PMID:
763348
DOI:
10.1038/278030a0
[Indexed for MEDLINE]

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