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Can J Ophthalmol. 1995 Apr;30(3):142-6.

Corneal epithelial fragility in diabetes mellitus.

Author information

1
Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Abstract

OBJECTIVE:

To assess corneal epithelial fragility in non-insulin-dependent diabetes mellitus (NIDDM) and its association with retinopathy.

DESIGN:

Survey.

SETTING:

University-affiliated hospital in Chandigarh, India.

SUBJECTS:

Seventy patients with NIDDM selected at random and 35 age-matched healthy control subjects recruited from hospital staff and their relatives.

MAIN OUTCOME MEASURE:

Corneal epithelial fragility, as measured with an esthesiometer.

RESULTS:

Mean corneal epithelial fragility values were significantly higher for the diabetic subjects without retinopathy than for the control subjects (p < 0.05). The mean epithelial fragility values for the eyes with diabetic proliferative retinopathy and those with nonproliferative retinopathy were significantly higher (by 84% and 41% respectively) than the mean value for the diabetic subjects without retinopathy (p < 0.05). There was no significant difference in mean epithelial fragility values between the proliferative and nonproliferative retinopathy groups.

CONCLUSIONS:

Eyes with diabetic retinopathy demonstrate increased corneal epithelial fragility.

PMID:
7627899
[Indexed for MEDLINE]

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