Format

Send to

Choose Destination
Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6906-10.

Three-dimensional functional magnetic resonance imaging of human brain on a clinical 1.5-T scanner.

Author information

1
National Institutes of Health In Vivo Nuclear Magnetic Resonance Research Center, Biomedical Engineering and Instrumentation Program, Bethesda, MD 20892, USA.

Abstract

Functional magnetic resonance imaging (fMRI) is a tool for mapping brain function that utilizes neuronal activity-induced changes in blood oxygenation. An efficient three-dimensional fMRI method is presented for imaging brain activity on conventional, widely available, 1.5-T scanners, without additional hardware. This approach uses large magnetic susceptibility weighting based on the echo-shifting principle combined with multiple gradient echoes per excitation. Motor stimulation, induced by self-paced finger tapping, reliably produced significant signal increase in the hand region of the contralateral primary motor cortex in every subject tested.

PMID:
7624341
PMCID:
PMC41439
DOI:
10.1073/pnas.92.15.6906
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center