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J Nat Prod. 1995 May;58(5):647-52.

Amphitoxin, a new high molecular weight antifeedant pyridinium salt from the Caribbean sponge Amphimedon compressa.

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Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli, Italy.


A new polymeric pyridinium alkaloid named amphitoxin [2] has been isolated from Amphimedon compressa, and its structure determined by spectroscopic analysis. In laboratory feeding experiments, crude extracts and purified amphitoxin [2] from A. compressa at lower than natural concentration levels effectively deterred feeding of a generalist predatory Caribbean reef fish, Thalassoma bifasciatum.

[Indexed for MEDLINE]

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