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Exp Mycol. 1995 Jun;19(2):163-5.

Resistance to azole drugs in Neurospora crassa.

Author information

1
T.H. Morgan School of Biological Sciences, University of Kentucky, Lexington 40506-0225, USA.

Abstract

Neurospora crassa was susceptible to azole drugs: ketoconazole (MIC 1 microgram/ml), fluconazole (MIC 5 micrograms/ml), and SCH39304 (MIC 5 micrograms/ml). Mutants of N. crassa resistant to ketoconazole were selected and genetically characterized. The seven characterized resistance mutations represented at least four genetic loci. Some mutants, but not all, were also resistant to fluconazole and to SCH39304.

PMID:
7614377
[Indexed for MEDLINE]

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