Format

Send to

Choose Destination
Trends Microbiol. 1995 Apr;3(4):155-9.

Mucosal immune responses to pneumococcal polysaccharides: implications for vaccination.

Author information

1
Dept of Cell Biology and Immunology, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands.

Abstract

Systemic vaccination does not effectively induce a protective immune response to Streptococcus pneumoniae infections in infants, elderly people and immunosuppressed patients, who are highly susceptible to this pathogen. As mucosal immune responses develop early in life and still function well in the elderly, mucosal vaccination (that is, by oral, intratracheal or intranasal routes) may be an alternative approach to current strategies.

PMID:
7613758
DOI:
10.1016/s0966-842x(00)88907-6
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center