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Trends Microbiol. 1995 Apr;3(4):149-54.

Bacterial translocation from the gastrointestinal tract.

Author information

1
Dept of Microbiology and Immunology, Louisiana State University Medical School, Louisiana State University Medical Center-Shreveport 71130, USA.

Abstract

Bacterial translocation is defined as the passage of viable indigenous bacteria from the gastrointestinal tract to extraintestinal sites, such as the mesenteric-lymph-node complex, liver, spleen and bloodstream. Three major mechanisms promote bacterial translocation: intestinal bacterial overgrowth, deficiencies in host immune defenses and increased permeability or damage to the intestinal mucosal barrier.

PMID:
7613757
DOI:
10.1016/s0966-842x(00)88906-4
[Indexed for MEDLINE]

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