Format

Send to

Choose Destination
Cell Biol Int. 1995 Jan;19(1):65-9.

A GCN-like response in Candida albicans.

Author information

1
Department of Molecular Biology, Lehigh University, Bethlehem, PA 18015, USA.

Abstract

The control of amino acid and purine biosynthesis in the yeast Saccharomyces cerevisiae is mediated by the transcriptional activator GCN4. We previously identified the presence of two putative GCN4 responsive elements (GCREs) in the promoter sequence of the Candida albicans ARO3 gene, which encodes an enzyme in the aromatic amino acid pathway. We now show that amino acid deprivation results in a dramatic rise in the steady-state level of ARO3-specific mRNA, indicative of a GCN-like pathway in C. albicans.

PMID:
7613513
DOI:
10.1006/cbir.1995.1009
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center