Format

Send to

Choose Destination
Curr Opin Nephrol Hypertens. 1995 Mar;4(2):130-8.

Renal involvement in hematological disorders: monoclonal immunoglobulins and nephropathy.

Author information

1
Department of Nephrology, Tenon Hospital, Paris, France.

Abstract

The study of monoclonal immunoglobulin-associated nephropathies is useful for analyzing the physicochemical properties of immunoglobulin components responsible for their deposition in the kidney. Notable advances include the first description of truncated heavy-chain deposition disease, characterization of protease resistance and binding properties of immunoglobulin light chains involved in myeloma-associated Fanconi's syndrome and cast nephropathy, and identification of hepatitis C virus as a plausible causative agent of the so-called essential mixed cryoglobulinemias.

PMID:
7600043
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center