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Genitourin Med. 1995 Aug;71(4):224-7.

Asymptomatic carriage of Haemophilus ducreyi confirmed by the polymerase chain reaction.

Author information

1
Department of Clinical Sciences, London School of Hygiene and Tropical Medicine, UK.

Abstract

OBJECTIVE:

To investigate asymptomatic carriage of Haemophilus ducreyi by using polymerase chain reaction (PCR) on samples from women at high risk of infection.

SUBJECTS:

213 commercial sex workers (CSWs) recruited in The Gambia, West Africa.

METHODS:

Genital samples (cervical, vaginal and ulcer) were tested for the presence of H ducreyi by PCR with the technique of "one tube nested primer".

RESULTS:

12 CSWs were PCR positive for H ducreyi; 8 of these women had genital ulcers on examination.

CONCLUSION:

Using a simplified PCR technique for detecting H ducreyi we have shown that 2% of CSWs were carrying the organism without clinical symptoms or signs. This has important implications for sexually transmitted disease control programmes in areas with a high prevalence of chancroid.

PMID:
7590712
PMCID:
PMC1195517
[Indexed for MEDLINE]
Free PMC Article

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