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Curr Biol. 1995 May 1;5(5):500-7.

Functions of fibroblast growth factors and their receptors.

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  • 1Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.


Fibroblast growth factors were first characterized twenty years ago as mitogens of cultured fibroblasts. Despite a wealth of data from experiments in vitro, insights have begun to emerge only recently on the normal function of these growth factors in mice and humans, as a result of studies of natural and experimental mutations in the factors and their receptors.

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