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Curr Opin Neurobiol. 1995 Jun;5(3):324-34.

Synaptic plasticity: hippocampal LTP.

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University of Laboratory of Physiology, Oxford University, UK.


One of the most intensively studied forms of synaptic plasticity is long-term potentiation (LTP). The past year has seen further evidence advanced on both sides of the presynaptic/postsynaptic locus of expression debate, without an obvious path to reconcile the two views. Real progress has been made, however, in clarifying the possible role of nitric oxide as a retrograde messenger and the cellular location of its synthetic enzyme. Intriguing glimpses of the complex involvement of metabotropic glutamate receptors in the induction of LTP have also appeared.

[Indexed for MEDLINE]

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