Format

Send to

Choose Destination
Curr Opin Genet Dev. 1995 Aug;5(4):492-8.

Signalling by hedgehog family proteins in Drosophila and vertebrate development.

Author information

1
Molecular Embryology Laboratory, Imperial Cancer Research Fund, London, UK.

Abstract

Members of the hedgehog gene family encode a novel class of secreted proteins and are expressed in embryonic cells known to possess important signalling activities in organisms as diverse as flies and chickens. Proteins of the hedgehog family act in these different developmental contexts as both permissive and instructive signals. How this signalling activity is transduced is (as yet) poorly understood, but recent studies point to the involvement of protein kinase A in both Drosophila and vertebrates.

PMID:
7580142
DOI:
10.1016/0959-437x(95)90054-k
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center