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Curr Opin Oncol. 1995 Jul;7(4):325-9.

Management of diarrhea induced by tumors or cancer therapy.

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Servizio di Oncologia Medica, Ospedale di Pesaro, Italy.


Diarrhea is a common event in the clinical history of cancer patients. It can be caused by the presence of tumor or it can be a side effect of treatment. The latter problem is occurring more often because new drugs (CPT-11) or drug combinations (fluorouracil plus interferon or leucovorin) have diarrhea as the dose-limiting toxicity. The clinical use of octreotide, a long-acting somatostatin analogue, seemed to demonstrate an improvement in most diarrheal states induced by tumors (endocrine tumors) or by treatments (short bowel syndrome; chemotherapy-induced diarrhea).

[Indexed for MEDLINE]

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