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Immunol Today. 1995 Oct;16(10):469-73.

Murine CD38: an immunoregulatory ectoenzyme.

Author information

1
DNAX Research Institute, Palo Alto, CA 94304, USA.

Abstract

CD38 is an ectoenzyme that utilizes NAD+ and is expressed by many cells of hematopoietic origin. Antibodies to CD38 potentiate many biological activities on lymphocytes, including induction of murine B-cell proliferation. In this article, Frances Lund and colleagues summarize information concerning the expression, enzymatic activity and signal transduction pathway utilized by murine CD38.

PMID:
7576049
[Indexed for MEDLINE]

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